Hello! you have reached the official blog spot of our lab which is based at the University of Texas Health Science Center at San Antonio, Department of Urology - our main area of study is prostate cancer, nutrition, and epigenetics - but we also study changes in gene expression in benign-prostatic hyperplasia - we have made this blog so as we can share thoughts about the lab, papers that are just published and anything else remotely relevant at any time, and from anywhere!
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Tuesday, August 30, 2011
new addition for the emergency reading list...
this is a case report, but the results are so dramatic I had to post it here: a prostate cancer patient with androgen independent disease failing docetaxel therapy had a PSA of 22ng/ml, and serum folate of 300nM. He revealed to his oncologist that he was taking a daily vitamin containing 400ug of folic acid, and in addition to B12 and porcine intrinsic factor, was taking methyl-folate (400ug per day). TWO WEEKS after dropping the vitamin supplements and avoiding the many foods fortified with folic acid, the patient's PSA began dropping, now at 2ng/ml - indicating a therapeutic response(!) - and now his serum folate is nearly 30-fold lower as well - read the whole report at http://www.jmedicalcasereports.com/content/pdf/1752-1947-5-413.pdf
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