Hello! you have reached the official blog spot of our lab which is based at the University of Texas Health Science Center at San Antonio, Department of Urology - our main area of study is prostate cancer, nutrition, and epigenetics - but we also study changes in gene expression in benign-prostatic hyperplasia - we have made this blog so as we can share thoughts about the lab, papers that are just published and anything else remotely relevant at any time, and from anywhere!
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Friday, January 20, 2012
Cooperative Dual-Activity Targeted Nanomedicine for Specific and Effective Prostate Cancer Therapy
Supra-magnetic nanoparticles combined with anti-PSMA antibodies and carrying paclitaxel result in a 20-fold increase in drug concentration at the target site - if this can be replicated in human subjects it would be a huge move forward for patients with prostate cancer - and perhaps even other cancers given that PSMA is expressed in most tumor neovasculature -- higher drug concentrations at the target tissue mean less side effects on non-target tissues -- read all about it here
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